The three-dimensional structures of proteins, antibodies, protein-small molecule complexes and antibody-antigen complexes can be analyzed by X-ray crystallography.
Service Overviews
The three-dimensional structures of proteins, antibodies, protein-small molecule complexes and antibody-antigen complexes can be analyzed by X-ray crystallography.
Service Contents
Service
Service Details
Client Provides
Deliverables and Standards
Time
Antigen/Antibody Structure Analysis
Protein preparation, protein crystal screening, and complex structure analysis
Protein or antigen/antibody sequences
Protein structure data files, experimental reports and raw data documents
3–4 months
Service Features
Sanyou crystal structure analysis combines the comprehensive application of protein preparation, crystal screening and crystal analysis. The service process is as follows:
Protein preparation: Target protein expression, purification, and activity validation.
Protein crystal screening: Large-scale crystallization and crystal screening of proteins for optimized protein crystals.
Complex structure analysis: Collection of X-ray diffraction data Data processing Three-dimensional analysis of target proteins.
Case Stastics
The screening results of a drug-target complex are shown below, with a structure resolution of 2 Å. The resolution is high and the results are reliable.